Autoscope-FDA TB: Automated AI assisted microscopy for live TB bacilli detection in sputum.

Autostain and Autoscope systems have been developed to enhance TB treatment monitoring in resource-limited settings. The Autostain system is an automated device for smear preparation and slide staining, using fluorescein diacetate (FDA) staining to detect viable Mycobacterium tuberculosis based on intracellular enzyme activity. By automating the staining process, Autostain improves reproducibility, reduces manual errors, and accelerates TB detection in microscopy-based workflows. It features automated reagent handling, minimized contamination risks, and a portable design, making it highly suitable for field applications. Moreover, its seamless integration with the Autoscope and AI-based TB detection systems further enhances diagnostic accuracy and efficiency.

The Autoscope is an AI-powered automated microscopy system designed to detect fluorescently labeled bacilli in clinical samples, such as sputum. It employs automated scanning and AI-assisted cell detection, significantly improving TB detection sensitivity and specificity. By integrating automated microscopy with AI-powered image analysis, the Autoscope delivers rapid, reliable TB diagnosis, reducing reliance on expert interpretation. Additionally, its integration with digital health systems enables real-time data reporting, patient tracking, and treatment monitoring, ensuring early intervention and better disease management.

Together, Autostain and Autoscope revolutionize TB diagnostics, especially in rural and resource-constrained settings. By leveraging automation, AI, and microscopy, these technologies enhance accessibility, efficiency, and accuracy, ultimately contributing to improved TB control and patient outcomes.